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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad154429cc0e097f8bc3401c3c87c43a2d3f28a18506755fc3fe378652fc2508' 
  AND token = 'hGi0Y9qmSovLxs8AbhCq2LMw7KPwI7fJyKAPTE1TZ48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}