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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1b33a47530a1a142e2229486020de38a77e3764144650a8760f20293fb7f7f' 
  AND token = 'KV0WczDxxfq5DOF5JUcd4/5ULT4WhUdnftaDYnbim3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}