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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ea0c72e593cf47bd15c6066b6b508dd8ac07fc52b8154a96e209b06806c91f' 
  AND token = 'wVivBdFxFwbAnWt3FoE0GQ5DFaXO84wfTP8hNdYZHEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}