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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f259264a3ecba5750da47a0d44ecbb4f29be3ed1666445f4e2f53b9acd7f18' 
  AND token = 'pDTCbX4H/lFIjf5tFha7+mRURcvi++k3PSZ0tzzjxoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}