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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2196338c21c9feeb41cadfa1b1a1018c61bb9cba41cd727ec566c50a6058c8fc' 
  AND token = 'tzuuV5PSQGv3h2QWfRzjU08tUaSP/mZNF8CHAb/PqnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}