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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10de00fc01f1f7680bb52db46edbc31187eda8ab573c256c7c2a0da61412b0da' 
  AND token = 'lpqaxQcvk1kkhjQ+M+ur7SWTU47fm0VMU18cWpT6reQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}