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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7f5237e0e1ef2a7c2b98527f1f5fa8b542adfcad0fda55e29973b6f0d49195' 
  AND token = 'BkUtDCP2R8+CQ6ftwvLnRnJYat3ZsGcf2n7dV7GTPuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}