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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434a07167337169eef4029b4eb7df8a55a36b66450266e2188f6a6ca7ecf8fe8' 
  AND token = 'fBKYBnERr1a9EGzNcy9tyFqZBc2l9C4HIR9NTUjqzJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}