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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '786f7fdb5c4339ad5161134cc4b80d76610c1eb66b1b75c6a5db308624dc363e' 
  AND token = 'LUfaus7GE6OcjjQ0gj2By5rURyHRyaQOzNQS7aBN3J4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}