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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5292d5e82c8e2dfd36fb2c0750043fac08b267529ccff7b63f3f7c2dae12e1b6' 
  AND token = 'cR0wWHuJywRv5SEkDMpOIhabD4geNq4gXe7mvyQbhzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}