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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7b3ca4f1d56c55b539fb9dd401ac60f39f12666172a819ac9f09f91d42c8dc' 
  AND token = 'Bq9g+IvG58EQamdtIjmmz5EQcnSYTvQMT7dC4mlVuR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}