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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a92b0143c9fe4f176dc07a0b3a54d0db59c9df0a0b73c3e39810c2453993a525' 
  AND token = 'mYws0R6UZ1eqBw3Sc9XyEYS4WBGdMAl35Tx9FfS5g5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}