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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229c2fd0e8389f70fe651577b6ef8c1fbaac10d58822323008bbd7f493bd35dd' 
  AND token = 'q4Ez/yDneqxXVysnB3SEHn4B1fpeIgRu+Ihcei4H+fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}