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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be31be9dd99ee31356c002c1d5af33ea22b24db853e9de040722a368811710f' 
  AND token = 'NIOcHpD/LvD+xM5S7NIj3dNDumfrC0JAE4vd5ZMqFmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}