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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a10d9b39096e2603fde40548dbe099ce23e850e3943f78c801e07737cf9ba1e2' 
  AND token = 'zP0XHOUiYpnVhCBvq3T8sZdC614v4ZJVoeAwb4sMVC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}