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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd13d84ce21550bf6679a7fda20dee11c2041ad9e790acdf8ea60633cbd6668bc' 
  AND token = 'L4EGyjD/KN7P36QJCEdV2kIxBwa/Pz/w4ybvfT7mj6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}