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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '675ab02750f6c14e1192657e4cc428711464c3cbdd63f8542b4726f0768b1898' 
  AND token = 'nGZaXG6uEKtuIoinXV1gSSt1cAtMKTkTSUNCP0yI4SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}