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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ac1f08d969618fb2415abbd8292c1cf38490f6d4e1d416c77a7380fbbdacaa' 
  AND token = '81P40chm0VvJ1OPEVmynLs9p9TMuKzxXdLEGhnE5i8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}