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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bd320427194a2d9494cf4c3f9da5570a135ac1d0ae4688a8dc358b9e4fb833' 
  AND token = 'Czi03hcO2aJUX+VzFY+gzgdJtxCS51zD8pi66zAmbRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}