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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4ab1007257771d52df1266f0b912da9b2a1dfbfaeadf903b3e7c43275f9ce5' 
  AND token = 'IpwK12ppvm2y5OkV2drrkktV5U+xxyHUOh5RfW4B0uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}