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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318d1ae5d40ef07b72a35f7f271ebbeb9ee49188f7a1b75da53315e005011868' 
  AND token = 'jmAPZdUliV288vt8LrnDyC38JEKUw8/NwvenUSXmFfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}