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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8e8a08ec065fd04e8073e49e59816c9fe7ea964b8e87ab0ac155b38ded7c4b' 
  AND token = '125S60d1JcZxYHZxFivxjPaQBLk1S8Nr5Tf9D+xwxo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}