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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afc10a39304b0118ae4fabb859c4f4aa0213ce34c4155769e5a215a56a740a2' 
  AND token = 'Fk6kl1CG+DBl88AjcqQHwJlfepqcO4C4xwHCNR74ZKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}