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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac74b44fea75d1f161ceaa7e0b8ac517a4381a28d5433f3e3d4fdc96e1908d07' 
  AND token = 'PlnsJbjTkG6Ohy3DXkV31Yy+Bw1kxVxsznV5WRjrkuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}