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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154846d4a0d577a8869637ab99426c169de84fe409023947aa5949e4200224cf' 
  AND token = 'rrnPCePDrnUTWgO9GowbOKjZ0v1W0JG4QVj0d29BWfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}