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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca2529449c16c8d2a89e9494cfe3280760c96e5d74e6eb773b10351188fc87d8' 
  AND token = 'PNLgaMC9+/+2xzEStbonI+qmSAWS60b+j4votteu+Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}