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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0af239ad23316d33d2b6269fca2c4abc8b2f9f492f98e07d8127701eb7b4e4' 
  AND token = 'o8ilhWQf/tqKc4fLoLrhFk25k425cxpmUKwc8tmBoyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}