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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac1a1a7efd096cb05f60a55af0a855802adb621d161bb7838815c8156595da62' 
  AND token = '8jTSGMHevVmyP1ItMZ8mE9oPC+EAXtiy5zvjNCJQWMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}