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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2e265f44821947c27a986e9b3c7b22c6b4c549a0d156914590c31c0c46f48a' 
  AND token = 'QUu+CXlASJnQ8gbNCDO7T5oW5wb48ST/PbSIKsC1/yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}