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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4f56221f9e5c897a89630644f3f451e3d0bd0b67c62f503595520f48db9e51' 
  AND token = 'RJ9wc9bc7T1FMbGaTQeQH29AzaujPl4/5uJjd19xjYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}