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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c0dd3bdc11b77b49555542c01c3aa066341b27bb7bb2608d03b5333e9111cd' 
  AND token = '1G4vrB3WFFi9pQP581Sm8OfAXDhcyL2rLXYYhCp9VQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}