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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb25e3fb495ae59f6032dba966e99f819d5ac4b1d58139f1a4ff7fa2d977060' 
  AND token = '3n+XDAXWWxE7+x1h+Xf2C03Nw+YpOzLBixpAKAh5ZiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}