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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '130ebf65b5f3c66c2d4a1e1920ef253778d1f205037363861f46a8652df6c92e' 
  AND token = 'e7Mez4oCeajTiNN/eBMsfHIczotBm70kC33zMv+EuPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}