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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de1ea5b98aac360f522ae4349291e59930f57bce21656ba13bd275fcc6bb4e1' 
  AND token = 'S0iNj3BzRNcoFYf0qznJXqnu3l4jciH3Q+TMK5Qy0Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}