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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e438140256a6602e977f82ca47fec1dc2fdef645f184071f70ed54928ceb055' 
  AND token = 'WXyCwZaEnfResN4UZOCloAC8nFeXcBy571/zRURm9wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}