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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4401e4fecd451119e10320d253372624edc49e1ff45e50c35fede256c0134dde' 
  AND token = 'TwY7Dv9JtpTCfvzS7oJNG3Utp3uGi5IXV6ZLww4ZVUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}