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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d223a90c543b2655e9d080d23a64d98d5bc2642db902a6eca0b9f5768510848' 
  AND token = 'Cz8oB5IKtpMW58e3gjSMSRb2B8vtphTRwaEWo0sa8lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}