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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8954cb43fb83a26475e62e4c198bcbf78fe4fcda4bf97312b134f06241e2b972' 
  AND token = '69mYns+KbAFnORM/YNWKKyd0YhUYFkZRzQOhbfbx1G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}