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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1d7b6c63742ab28a2aa15fcf58e453a11a68c09dcef958ff9dfb828f7cbd665' 
  AND token = 'kK40qFLRJc9YIQVrCyE7GGV346ezhh6fJ4y2+NcqQCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}