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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5295f86088ae3085839e59905210e6051bd9f987fce2bbb7b0b8a10f81771b3b' 
  AND token = 'UNOzy6fVdmX3bOXuJBTclK4Rwc8HZxa9L0sOft69Pc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}