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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4e948f909c938ac681094e2bc2a0b4e86891bf58be2df1e7d7a68a8061f48b' 
  AND token = 'DYJCo456uXQ1FOCMRzfVwpTqVHRwFMAXpzV6CaYPzKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}