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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6ac605c3d2da277ffdfe5ac0cb74b74d8cc231fe5f82bd7d424e7e6cdac1a2' 
  AND token = 'wWFMQanqtuw5AV3o3zxRPFW5OruoLW4IdlovbfkUBq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}