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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d7c1536795803ce69e5b5fb4c98b8ee7b80d4d4f9280a5eac6974698dcf675f' 
  AND token = '+4rrKCs112GAz0fB4EP24866vS6OQv5Ze01OWKTJcJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}