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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323ec79836c3c162b075d2e6fb6e3c44e94a0d8756ab388489fd38116f71a002' 
  AND token = '2WIs0TlH3PyQRVZbJIO5ZYVQwN3HwKVH4EP3GNDzNvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}