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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3639489846b7f963185d6d5ff8d9dcc702aff62d8e3a71f38c242f989acc6e48' 
  AND token = 'VX9qDEKkd4VvHPdpYWtgagzt8VHBNowVyI8spNneixk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}