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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b35640d99be8b285f911cde039d2ccaf65a719ffd395592ec47391308a4ef2' 
  AND token = 'kv3Qs2gJRZbpR8IPsx8eL8EfB1BxfQxBibMHSSFdKLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}