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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0642d0d2fe9008bb46901b7eabb8aa1095a7b2971571858a32b1cc5dc7ca9480' 
  AND token = 'VPKcixSeFwzwbRLL6zL4eTK4c3R2hekwuHSTR7hU0LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}