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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff1ea525342549ba2211ef72be6e1e65b0822e0e57bf382ece7567bc328973d' 
  AND token = '+jvw+Z3Uzi48SUn27zAiNVvbxhzqkQIhKHfwaaah23Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}