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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b273fc33de4d29ad65cd5e2110fc3ad26ae1ecb90d906c251687726b4c33e3b' 
  AND token = 'NOapqnus7pdlGIQB2NoAba8DtvSMIvHRm/u6TvAwbnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}