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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf40bde40cc572bcd708515020faadc1d4d7da0fefed84c3bd2dd36076b6fd9f' 
  AND token = 'vmtXF61yzzhmpxTsfk3M/GuesbEcnYzP8PMiwFB1JIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}